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DNA Replication, Second Edition

Arthur Kornberg Stanford University
Tania A. Baker Massachusetts Institute of Technology

Often imitated but never rivaled, DNA Replication, Second Edition, regarded around the world as a classic of modern science, is now back in print in a paperback edition.

Print Book, ISBN 978-1-891389-44-3, US $134
eBook, eISBN 978-1-938787-23-3, US $94
Publish date: 2005
932 pages, Softbound


Often imitated but never rivaled, DNA Replication, Second Edition, regarded around the world as a classic of modern science, is now back in print in a paperback edition. Kornberg and Baker’s insightful coverage of DNA replication and related cellular processes have made this 1992 edition the standard reference in the field.


List of Adoptions

Table of Contents

Chapter 1: DNA Structure and Function
Chapter 2: Biosynthesis of DNA Precursors
Chapter 3: DNA Synthesis
Chapter 4: DNA Polymerase I of E. coli
Chapter 5: Prokaryotic DNA Polymerases Other Than E. coli Pol I
Chapter 6: Eukaryotic DNA Polymerases
Chapter 7: RNA Polymerases
Chapter 8: Primases, Primosomes, and Priming
Chapter 9: Ligases and Polynucleotide Kinases
Chapter 10: DNA-Binding Proteins
Chapter 11: DNA Helicases
Chapter 12: Topoisomerases
Chapter 13: Deoxyribonucleases
Chapter 14: Inhibitors of Replication
Chapter 15: Replication Mechanisms and Operations
Chapter 16: Genome Origins
Chapter 17: Bacterial DNA Viruses
Chapter 18: Plasmids and Organelles
Chapter 19: Animal DNA Viruses and Retroviruses
Chapter 20: Regulation of Chromosomal Replication and Cell Division
Chapter 21: Repair, Recombination, Transformation, Restriction, and Modification
Chapter 22: Synthesis of Genes and Chromosomes


“Together, the authors have created a text that should become a classic in science. DNA Replication is much more than a summary of the field: it is an excellent reference book on DNA and nucleic-acid enzymes, and every molecular laboratory should have a copy for easy access to the principles underlying today’s DNA technology…The book is an excellent resource for graduate teaching and should also be a useful source of background material for undergraduate courses in biochemistry…In areas that I know best, I was impressed by the accuracy of the information and the thoughtfulness of the discussions.”
-Nature, Review by Sue Wicker, NIH

“Authoritative yet lucid accounts of a dynamic and ever-expanding field…students and experts alike should benefit from having a desk copy.”
-J. Wang, Harvard University

Arthur Kornberg

Arthur Kornberg Stanford University

Arthur Kornberg shared (with Severo Ochoa) the Nobel Prize in Medicine in 1959 for his laboratory synthesis of DNA. He is the author of several major books, including DNA Replication, second edition (W.H. Freeman and Company, 1991) and a scientific autobiography, For the Love of Enzymes: the Odyssey of a Biochemist (Harvard University Press, 1989). He is Professor Emeritus of Biochemistry at the Stanford University School of Medicine.

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Tania A. Baker

Tania A. Baker Massachusetts Institute of Technology

Tania A. Baker obtained her training in biochemistry with Dr. Kornberg at Stanford University. She is the E.C. Whitehead Professor of Biology at Massachusetts Institute of Technology and Investigator at the Howard Hughes Medical Institute. She is also a co-author of the internationally best selling text, Molecular Biology of the Gene, Fifth Edition.

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