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Student Solutions Manual to accompany Modern Physical Organic Chemistry

Michael Sponsler Syracuse University
Eric V. Anslyn University of Texas, Austin
Dennis A. Dougherty California Institute of Technology

This Student Solutions Manual, which provides complete solutions to all of the nearly 600 exercises in the accompanying textbook, will encourage students to work the exercises, enhancing their mastery of physical organic chemistry.

ISBN 978-1-891389-36-8
eISBN 978-1-938787-77-5
Copyright 2005
368 Pages, Paper


This Student Solutions Manual, which provides complete solutions to all of the nearly 600 exercises in the accompanying textbook, will encourage students to work the exercises, enhancing their mastery of physical organic chemistry. When used properly by students to compare their solutions with the detailed solutions provided in the manual, it will serve as an excellent tool for sharpening skills and encouraging a deeper understanding of the concepts that are covered. Like the accompanying text by Anslyn and Dougherty, this manual also includes Going Deeper highlights on selected topics, where students can explore exceptions to the rule, discover surprising connections between topics, and gain insights into practical aspects of the material. Problem-solving strategies will be enhanced by students’ coordinated use of the textbook and this manual.

Link to Textbook

Table of Contents

Chapter 1: Introduction to Structure and Models of Bonding, Solutions

Chapter 2: Strain and Stability, Solutions

Chapter 3: The Thermodynamics of Solutions and Noncovalent Binding Forces, Solutions

Chapter 4: Molecular Recognition and Supramolecular Chemistry, Solutions

Chapter 5: Acid-Base Chemistry, Solutions

Chapter 6: Stereochemistry, Solutions

Chapter 7: Energy Surfaces and Kinetic Analyses, Solutions

Chapter 8: Experiments Related to Thermodynamics and Kinetics, Solutions

Chapter 9: Catalysis, Solutions

Chapter 10: Organic Reaction Mechanisms Part 1: Reactions Involving Additions and/or Eliminations, Solutions

Chapter 11: Organic Reaction Mechanisms Part II: Substitutions at Aliphatic Centers and Thermal Isomerizations/Rearrangements, Solutions

Chapter 12: Organotransition Metal Reaction Mechanisms and Catalysis, Solutions
Chapter 13. Organic Materials Chemistry, Solutions

Chapter 14. Advanced Concepts in Electronic Structure Theory, Solutions

Chapter 15: Thermal Pericyclic Reactions, Solutions

Chapter 16: Photochemistry, Solutions
Chapter 17: Electronic Organic Materials, Solutions


View Contents and Preface in PDF Format
View Sample Chapter (6) in PDF Format
To the Student


Michael Sponsler Syracuse University

Michael B. Sponsler earned his PhD from the California Institute of Technology in 1987, working as an NSF Graduate Fellow with Dennis A. Dougherty. He did research as an NIH Post-doctoral Fellow with Robert G. Bergman at the University of California, Berkeley and then accepted a faculty position at Syracuse University in 1989, where he is now Associate Professor. His research involves physical organic studies in the diverse areas of conjugated organometallic complexes and liquid crystalline holographic recording materials. The organometallic studies include synthesis and characterization of both mixed-valence complexes with polyenediyl bridges and related polymers. Applications in molecular electronics and nanotechnology are under investigation. The holographic studies are focused on new strategies for producing electrically switchable holograms.

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Eric V. Anslyn University of Texas, Austin

Eric V. Anslyn received his PhD in Chemistry from the California Institute of Technology under the direction of Robert Grubbs. After completing post-doctoral work with Ronald Breslow at Columbia University, he joined the faculty at the University of Texas at Austin, where he became a Full Professor in 1999. He currently holds four patents and is the recipient of numerous awards and honors, including the Presidential Young Investigator, the Alfred P. Sloan Research Fellow, the Searle Scholar, the Dreyfus Teacher-Scholar Award, and the Jean Holloway Award for Excellence in Teaching. He is also the Associate Editor for the Journal of the American Chemical Society and serves on the editorial boards of Supramolecular Chemistry and the Journal of Supramolecular Chemistry. His primary research is in physical organic chemistry and bioorganic chemistry, with specific interests in catalysts for phosphoryl and glycosyl transfers, receptors for carbohydrates and enolates, single and multi-analyte sensors – the development of an electronic tongue, and synthesis of polymeric molecules that exhibit unique abiotic secondary structure.

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Dennis A. Dougherty California Institute of Technology

Dennis A. Dougherty received a PhD from Princeton with Kurt Mislow, followed by a year of postdoctoral study with Jerome Berson at Yale. In 1979 he joined the faculty at the California Institute of Technology, where he is now George Grant Hoag Professor of Chemistry. Dougherty's extensive research interests have taken him to many fronts, but he is perhaps best known for development of the cation-π interaction, a novel but potent noncovalent binding interaction. More recently, he has addressed molecular neurobiology, developing the in vivo nonsense suppression method for unnatural amino acid incorporation into proteins expressed in living cells. This powerful new tool enables “physical organic chemistry on the brain” - chemical-scale studies of the molecules of memory, thought, and sensory perception and the targets of treatments for Alzheimer's disease, Parkinson's disease, schizophrenia, learning and attention deficits, and drug addiction. His group is now working on extensive experimental and computational studies of the bacterial mechanosensitive channels MscL and MscS, building off the crystal structures of these channels recently reported by the Rees group at Caltech.

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